In 2022, we again raised funds through our Spinal Research Hero Month, for some very important research – the ‘ASRF Case Report Project’. This exciting project has been designed to gather front-line evidence in the form of case study information, from Chiropractors around the globe. This project has resulted in a collection of published and…
Basic science evidence suggests that chiropractic adjustments modulate immune mediators in healthy individuals in the short term and cortisol levels in symptomatic and asymptomatic individuals. However, clinically relevant research has not yet been done. The purpose of this study is to determine whether there is an association between regular chiropractic care and immune status. Two…
The pupil diameter, controlled by sympathetic and parasympathetic innervation, is a direct reflection of autonomic nervous system (ANS) activity. This study aims to investigate the clinical feasibility of using pupillary activity measured with a cost-effective eye tracker as a measure of ANS function in people under chiropractic care. Computerised pupillometry is a low cost, non-invasive…
Chiropractic adjustments have a positive impact on various aspects of central and autonomic nervous system function, in particular, a single session of chiropractic adjustments has been shown to alter pre-frontal cortex (PFC). However, how chiropractic adjustments impact PFC activity under stress has not been explored. This proposed pilot study aims to evaluate the feasibility of…
In 2021, we raised funds through our Spinal Research Hero Month, for some very important research – the inaugural ‘ASRF Case Report Project’. This exciting project has been designed to gather front-line evidence in the form of case study information, from Chiropractors around the globe. This project has resulted in over 30 published and indexed…
Multiple sclerosis (MS) is an inflammatory autoimmune disease associated with an imbalance between pro- and anti-inflammatory cytokines resulting in a demyelinating and neurodegenerative disease. There is moderate quality evidence that spinal manipulation (SM) is better than control in influencing cytokine activity in asymptomatic individuals, but few studies have been completed in individuals with chronic inflammatory…
This study will expand previous suggestive work in the literature [1-6] to explicitly determine whether immune function can be improved after a series of spinal manipulative therapy (SMT) sessions. The primary aim is to investigate and measure the impact of reducing vertebral subluxation on immune cell function. Before and after 12 weeks of prescribed chiropractic…
The overall goal of this PhD project is to develop the understanding of chiropractic practice through mixed methods research, and to inform systematic controlled studies in the field of chiropractic, specifically pertaining to vertebral subluxation-based research. This proposal seeks to assist the profession in its understanding of individual philosophies and how this relates to how…
Correcting vertebral subluxations lies at the heart of chiropractic practice. Most chiropractic techniques emphasise the importance of a thorough spinal examination in order to locate and analyse vertebral subluxations and determine the most appropriate approach to facilitate their correction. Yet, no research exists that clearly shows that specific spinal adjustments are of more benefit to…
This preliminary clinical trial will examine the effects of vagal nerve activation via cervical chiropractic adjustments on clinical outcomes in patients with colon cancer. Specifically, we hypothesize that participants randomly assigned to receive cervical chiropractic adjustments will have higher heart rate variability (HRV), better health-related quality of life (QOL) and lower levels of both pain…